Dale Malony: Some people are allergic to bee stings
and their body reacts dangerously to them. Would that be because
there’s something about bee stings that makes them particularly toxic
for that individual, or something that makes their immune system…
Dr. Padgett: No. There’s something in that
allergen that the body cannot defend against.
Dale Malony: Okay, so no matter how hard it tries it
still can’t get rid of it.
Dr. Padgett: Right. And so you react to the
allergen. Same thing with fleas or dust or whatever you’re allergic
to. And we’re allergic to the same types of things our dogs are
allergic to.
Debbie Martin Question: If you have a family of dogs
that are allergic to one thing, say something in the food, and then
you removed that food and don’t see an expression of that disease
anymore. Then another generation or two down you start seeing
different problems. Would that fit your description?
Dr. Padgett: No. If you
have a gene for an allergy, that gene is going to stay for that
allergen. Now that might be expressed a lot of different ways. Like
you could be allergic to dust, for example, and you can get the dust
from the carpet one time, and then the bed the next time, and so you
might not relate the two circumstances, but the allergy stays the
same. Genes don’t just change overnight. They’ll stay exactly the
same.
Joanne Chanyi: I think what Deb’s trying to say is
like one of our dogs is allergic to soybeans, so we all stopped
feeding soybean for food. Well, lately we’ve been having ear
infections or other skin problems.
Dr. Padgett: I would not relate them unless
some way or another soybeans are getting in to their diet. I mean
that’s possible.
Joanne Chanyi: Usually when soybeans are in the
dog’s treats, you get redness in the skin and they loose all the hair
on the back. But these are extreme cases.
Dr. Padgett: Different system. Different
problem. That’s my opinion. You know I’m not God, I can’t tell you
that for sure, but I can tell you for sure that genes don’t change. So
if you have an allergy to soybeans that’s not going to give you an
allergy to sweet peas.
Debbie Martin: And it would still be an allergic
dog?
Dr. Padgett: Sure, it’s an allergic dog. You
just took away the allergic influence. What you’ve done is alter a
genetic disease environmentally. And that dog will transmit allergies
to soybeans to its offspring. I mean you’re not seeing it anymore but
you feed the offspring’s soybeans and you’ll see it.
Others’ Questions: Can allergies be developed in a
non-allergic…genetically, non-allergic dog? Are all allergies genetic?
Dr. Padgett: That is the question that it
comes too. What happens with some genetic diseases is you need enough
stimuli to trigger it. You almost never will react to anything the
first two, three, four times… you’re exposed to an allergen, but then
you get it severely. Then if you keep using that allergen, it gets
really, really bad.
Joanne Chanyi: And also if you stay away from it.
I’m allergic to a lot of things that I’ve stayed totally away from for
five or six years, and now I can tolerate them. But just in little
bits…not overindulge.
Dr. Padgett Reply: Sure, sure... Allergies
are probably divided into multiple individual diseases and not lumped
together under the term allergy. They’re not all going to be in the
same disease, but let’s look at them.
Say if 45 percent are affected with allergies
(considering all allergies related, for the sake of argument), then
probably 75 percent are carriers. You’re then at the point where the
Hardy-Weinberg law turns in on itself, you’re at a limit. At 50
percent affected, the Hardy-Weinberg law won’t work because you don’t
have any non-carriers left for breeding. Every mating has to have an
affected dog in it. So if 45 percent are affected, then probably only
10 or 12 percent of the dogs are genetically normal for that set of
traits. That will change if we look at each disease individually. Like
the problem with the soy is an individual disorder.
Debbie Martin: So basically what you’re saying is if
we have a dog that’s got food allergies we could breed it to a dog
that has inherited allergies and block it?
Dr. Padgett: And block it.